Programme 1: Simon Mead: Targeted genotyping of candidate SNPs identified by exome sequencing as potential risk factors for Creutzfeldt-Jakob disease

Programme 2: Parmjit Jat: Uncoupling infectivity and toxicity in in vitro models of prion-induced toxicity.

Programme 3: Emmanuel Asante: Transgenic modelling of a novel inherited prion disease associated with PRNP Y163X mutation

Programme 4: Peter Klöhn: Identifying the prion interactome in prion-infected cells

Programme 5: Graham Jackson: Structural and biochemical features that differentiate prion protein amyloid from prion infectivity

Programme 6: Jonathan Wadsworth: Structural characterisation of mammalian prions

Programme 7: Jan Bieschke: Structure and dynamics of prions and their ligand interactions

Programme 8: Director: Development of a probe for prion protein ligand binding and propagation