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MRC Prion Unit
From fundamental research to prevention and cure

2017 Publications

Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation. 
Clayton EL, Mancuso R, Nielsen TT, Mizielinska S, Holmes H, Powell N, Norona F, Larsen JO, Milioto C, Wilson KM, Lythgoe MF, Ourselin S, Nielsen JE, Johannsen P, Holm I, Collinge J; FReJA., Oliver PL, Gomez-Nicola D, Isaacs AM. Hum Mol Genet. 2017 Jan 16. doi: 10.1093/hmg/ddx003. [Epub ahead of print]

Cultural factors that affected the spatial and temporal epidemiology of kuru. 
Whitfield J. T., Pako, W. H., Collinge, J. & Alpers, M. P. (2017) R Soc open sci

Neuroanatomical correlates of prion disease progression - a 3T longitudinal voxel-based morphometry study. 
De Vita E, Ridgway GR, White MJ, Porter MC, Caine D, Rudge P, Collinge J, Yousry TA, Jager HR, Mead S, Thornton JS, Hyare H.  Neuroimage Clin. 2016 Nov 2;13:89-96. eCollection 2017.